Amperos Health Secures $4.2M Seed Round to Revolutionize AI Medical Billing with Amanda
June 18, 2025
byFenoms Startup Research
In a significant move for the healthtech industry, Amperos Health, a pioneering startup in AI-driven medical billing, has announced a successful $4.2 million seed funding round. The funding round was led by top-tier investors including Uncork Capital, Neo, Nebular, and prominent angel investors from OpenAI, Twilio, and Stripe.
At the heart of Amperos Health’s innovation is Amanda, an AI biller designed specifically to streamline the arduous process of handling medical denials and collections. With healthcare providers consistently challenged by administrative inefficiencies, Amanda offers a bold, tech-forward solution to reduce costs and improve claim resolution rates without the need for additional staff.
What is Amperos Health?
Amperos Health is a healthtech startup focused on solving one of the most pressing operational pain points in the medical industry: claims denials and collections. With billions lost annually due to delayed or denied reimbursements, the need for smarter billing processes is more urgent than ever. Amperos tackles this challenge by leveraging artificial intelligence to automate billing workflows, ensuring faster, more accurate collections with fewer human resources.
Founded by Michal Miernowski, the company is positioning itself as a disruptor in the AI medical billing space. Their AI tool Amanda doesn’t just identify issues
it actively resolves them, mimicking the expertise of a seasoned medical biller but working at the speed and scale only technology can deliver.
Amanda: The AI Biller for Denials and Collections
At the center of Amperos Health’s offering is Amanda, a purpose-built AI assistant designed to manage medical denials and collections. Amanda’s role is direct and results-driven: resolve more denials and collect more outstanding claims - without hiring more staff.
Her core capabilities include:
- Automated Denial Resolution that flags errors, appeals denials, and tracks progress automatically.
- Predictive Collection Targeting that uses data to prioritize which claims to pursue first.
- Native Integration with EHRs and billing systems to ensure no workflow disruption.
- Massive Throughput, allowing Amanda to process thousands of claims in parallel, something even large human billing teams struggle with.
And this couldn’t come at a more urgent time. According to the American Hospital Association, U.S. hospitals lose over $262 billion annually due to denied claims. On average, hospitals experience a denial rate of 9%, with nearly two-thirds of those denials being recoverable - if only they had the right systems in place.
This is where Amanda fits in like a scalpel.
What’s striking - especially for other healthtech or enterprise AI founders watching - is how focused Amanda is on a cash flow choke point. It’s not just automation for the sake of efficiency; it’s automation pointed exactly where money is stuck in the system.
Too often, early-stage companies build general-purpose tools or assistants that demo well but never align with real business friction. Amperos went the other way. They found a workflow where hospitals are bleeding revenue - denials and collections - and built directly into that pressure point. Not around it. Not adjacent to it. Into it.
This is the difference between AI as a feature and AI as a revenue unlock.
Amanda doesn’t just automate work; she recovers cash. She does what any founder should aim for: create a product that makes the buyer money, not just saves them time. That changes the entire sales conversation - from “nice to have” to “how fast can we deploy this?”
And the demand is real. The global healthcare revenue cycle management (RCM) market is projected to grow to $256.3 billion by 2030, up from $121.4 billion in 2022, according to Precedence Research. The market is being driven by the need to reduce administrative costs, improve payment accuracy, and keep up with an increasingly complex billing landscape. AI-powered tools like Amanda are not just a trend - they’re fast becoming a necessity.
Because Amanda works inside existing billing stacks, she sidesteps one of the biggest barriers to adoption in healthcare: workflow disruption. She’s not a dashboard, not a platform, not another tool to learn - she’s an extra teammate who just happens to be an AI. That’s what makes her sticky.
A Vote of Confidence: Backing from Elite Investors
Raising $4.2 million in seed capital is no small feat - especially in today’s competitive tech funding landscape. The fact that Amperos attracted investors from OpenAI, Twilio, and Stripe speaks volumes about the company’s potential. These are some of the world’s most forward-thinking technology companies, and their early involvement suggests that Amperos Health is poised for significant impact.
Leading the round were:
- Uncork Capital – Known for backing early-stage startups with high-growth potential.
- Neo – A venture firm with a keen interest in next-gen AI and automation.
- Nebular – Focused on supporting future-defining technologies in healthcare and enterprise.
This robust investor lineup not only provides capital but also opens doors to valuable industry connections and strategic guidance.
The Future of AI in Medical Billing
The U.S. healthcare system is notoriously complex, with hospitals and clinics losing billions annually due to denied claims. Traditional billing teams are often understaffed, overwhelmed, and reliant on outdated processes. This is where AI medical billing solutions like Amanda become game-changers.
By automating the claims resolution process, Amanda helps healthcare providers:
- Increase revenue recovery
- Reduce the average time-to-payment
- Improve patient satisfaction by reducing billing errors
- Lower operational costs
With AI increasingly being adopted across industries, the medical billing sector is ripe for disruption. Amperos Health’s Amanda could set a new standard for how claims are processed and payments collected.
What’s Next for Amperos Health?
With this new infusion of capital, Amperos Health plans to:
- Expand its engineering and AI development teams
- Enhance Amanda’s capabilities through machine learning improvements
- Deepen integrations with popular billing and EHR platforms
- Accelerate go-to-market efforts and customer acquisition
According to founder Michal Miernowski, the goal is not just to reduce friction in medical billing but to empower healthcare providers to focus more on patient care and less on administrative headaches.