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Trogenix Raises $94.3 Million in Series A to Pioneer RNA-Based Therapeutics for Inflammatory and Autoimmune Diseases

Trogenix, a UK-based biotechnology company, has secured $94,323,600 in Series A funding, a major milestone in its mission to redefine RNA-based medicine. The round was led by IQ Capital, with participation from Eli Lilly and Company, Meltwind, LongeVC, and Calculus Capital.

This significant investment will accelerate Trogenix’s expansion of its RNA modulation platform, support its first-in-human clinical trials, and enable the company to advance its pipeline of therapies targeting inflammatory and autoimmune disorders - conditions that have long lacked durable, mechanism-driven treatments.


Building Precision at the Molecular Level

RNA therapeutics have emerged as one of the most promising frontiers in medicine. Yet, most efforts have focused on vaccines and transient gene expression. Trogenix takes a different approach. Its proprietary technology is designed to modulate immune responses directly at the molecular level, creating precise interventions that retrain the body’s own biology.

The company’s platform integrates synthetic RNA constructs, intelligent delivery systems, and immune-cell programming to control how genes are expressed and how inflammation manifests. The goal is not just to mute immune dysfunction, but to restore natural immune balance - a step toward achieving remission rather than symptom control.


A Science-Led Team with Deep Immunology Roots

Behind Trogenix is a multidisciplinary team combining expertise from molecular biology, synthetic chemistry, and translational medicine. Under the leadership of Founder and CEO Ken Macnamara, the company has built a platform designed for adaptability and repeatability, two factors that increase the speed of preclinical discovery and de-risk the development process.

Macnamara’s guiding principle has been clear from the start: RNA is not just a molecule - it’s a programmable tool for healing. His background in immunology and computational biology has shaped Trogenix’s philosophy of engineering therapies that can “learn” from cellular interactions, a leap forward in how medicine interfaces with living systems.


Investors Backing the RNA Revolution

Trogenix’s Series A investors bring both capital and strategic alignment. IQ Capital, a UK-based deep-tech venture firm, led the round with its track record of supporting disruptive science startups. Eli Lilly and Company, a global pharmaceutical leader, adds critical domain knowledge and future partnership potential in RNA and immunology.

Meltwind, LongeVC, and Calculus Capital complete the investment syndicate, offering cross-border networks and growth expertise in life sciences. Collectively, this group represents an ecosystem of scientific conviction and commercial acceleration - a combination critical for scaling biotech innovation.


Scaling Lessons That Matter

Trogenix’s trajectory highlights a key insight for biotech founders: innovation isn’t just about discovery - it’s about platform design. Instead of focusing on a single therapeutic target, the company engineered a modular RNA system capable of generating multiple drug candidates from one technological core.

This approach reflects a new biotech thesis: platforms create pipelines, and pipelines create durability. By building its foundation around reusability and flexibility, Trogenix has set itself up to compound discoveries into sustainable market value.

For early-stage biotech founders, this is a powerful model - build scalable architectures, not isolated experiments. The most enduring deep-tech ventures are those that evolve into infrastructure, shaping entire therapeutic categories rather than chasing singular breakthroughs.


RNA Medicine in a Global Context

The global RNA therapeutics market is projected to surpass $38.5 billion by 2030, growing at a CAGR of 12.8% (Grand View Research, 2024). While the public spotlight has primarily focused on mRNA vaccines, a new wave of innovation is emerging in RNA interference (RNAi), antisense oligonucleotides, and RNA editing - areas Trogenix is actively advancing.

This shift reflects a broader transformation in biotechnology: moving from generalized treatments to programmable precision medicine. As chronic diseases rise and personalized care becomes the norm, companies capable of building adaptable RNA platforms will shape the next decade of drug development.


What’s Next for Trogenix

With this Series A funding secured, Trogenix plans to expand its R&D operations, grow its clinical team, and initiate early-stage human studies. The company will also strengthen collaborations with research institutions and pharmaceutical partners, ensuring its innovations can move efficiently from lab to patient.

Trogenix’s long-term vision is to establish RNA as a cornerstone of immunotherapy, enabling precise, reversible, and durable control of complex diseases. Its mission transcends incremental drug development - it aims to transform how medicine interacts with human biology at the code level.


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